We provide comprehensive HPLC screening of chiral stationary phases from diverse manufacturers to ensure the achievement of appropriate selectivity and quantitation limit. We conduct screening on normal and reverse-phase, polar organic and polar ionic modes, providing a mobile phase array that covers a wide range of polarities. Mobile phase additives are often used based on the structural features of the target. We also offer chiral SFC method development as a complement to chiral HPLC, mostly focusing on applications for preparative resolution processes.

We perform qualification of chiral chromatographic methods based on ICH guidelines. The chiral method can be used for the quantitative or qualitative determination of chiral and diastereomeric purity of drug substances, drug products, intermediates and raw materials and for monitoring resolution processes.