AMRI’s unique and efficient fermentation processes speed supply of natural product leads and analogs for practical, scalable processes. At our cutting-edge facilities, we adhere to cGMP fermentation procedures, ensuring process safety and product quality and purity.

Leverage our fermentation capabilities for a variety of applications, such as:

  • Natural products production
  • Biotransformations to complement classical chemistry
  • Hydroxylations to enable new chemical routes
  • Asymmetric syntheses and chiral resolutions
  • Practical bioprocess development and improvement

We offer global capacity for full fermentation, semi-synthesis and enzymatic process development, including:

  • More than 40,000 purified biocatalysts and strains
  • Expertise with diverse strains, especially eubacteria, fungi and yeasts
  • Broad experience with numerous biocatalyst classes (hydroxylating, redox, halogenating, stereoselective)
  • Predetermined phylogenetic and biotransformation capabilities of biocatalysts
  • Proprietary parallel mini-fermenters and bioreactors with design of experiments
  • High-throughput analytical systems, including liquid chromatography/mass spectrometry (LC/MS) and chiral high-performance liquid chromatography (HPLC)
  • Proven technology transfer procedures and scale-up from mL to 500 L
  • Extensive downstream separations and chemistry integration