The water sorption/desorption profile of a solid provides key information about the physical stability of solid forms, especially hydrates. Our experts investigate the moisture uptake of samples at various relative humidities and temperatures using moisture sorption balances and/or gravimetric methods, and we can fully characterize any new forms observed. This technique may also be used to quantitate amorphous material in drug substance.

Organic Vapor Sorption and Desorption

We can perform organic vapor sorption to provide information on solvated forms and for quantitation when water sorption may not be appropriate. In addition, our scientists can assess the physical stability of amorphous materials using various organic vapors.