October 3, 2018
- Human liver microsomes.
- Human CYP isoforms responsible for metabolism of test compound determined by measuring metabolism suppression in the presence of CYP isoform-selective inhibitors.
|Test Compound Concentration||1 µM|
|Incubation Time||30 minutes|
|Positive Control||CYP isoform-selective probe substrates|
|Number of Repeats||2|
Study Report: Percent of metabolism of test compound suppressed by CYP isoform-selective inhibitors.
Test Compound Requirement: 2-3 mg dry powder or 100-200 µL of 10 mM DMSO stock solution.