Fermentation

AMRI’s unique and efficient fermentation processes speed supply of natural product leads and analogs for practical, scaleable processes.

Typical applications include:

• Natural Products Production
• Wide variety of biotransformations to complement classical chemistry
• Hydroxylations to enable new chemical routes
• Asymmetric Syntheses and chiral resolutions
• Practical bioprocess development and improvement
  

Capabilities for full fermentation, semi-synthesis, and enzymatic process development come from:

• An extensive collection of >40,000 purified biocatalysts and strains
• Broad experience with diverse strains, especially with eubacteria, fungi, and yeasts
• Broad experience with numerous biocatalyst classes (hydroxylating, redox, halogenating, stereoselective)
• Predetermined phylogenetic and biotransformation capabilities of biocatalysts
• Proprietary parallel mini-fermentors and bioreactors with D.O.E.
• High throughput analytical systems (including LC/MS and chiral HPLC)
• Scale-up from mL to 500-L
• Proven technology transfer procedures
• A dedicated server for complete process records
• Extensive downstream separations and chemistry integration