Bioanalytical Services

AMRI develops and executes rapid, sensitive, and robust bioanalytical methods for extraction and quantitation of drug and metabolites in biological fluids and tissues, to support preclinical and clinical studies.

AMRI Advantage

• Biological sample preparation

• Extensive expertise with diverse drugs and complex biological matrices, including plasma, urine, feces, bile, and various specific organs and tissues

• Rapid selection and method development from numerous options for analyte extraction and recovery

• Quantitative Bioanalysis

• Rapid method development for quantitative LC/MS/MS analysis

• Radiometric detection for radiolabeled drug and metabolites

• Calculation and modeling of pharmacokinetic parameters

• Overall mass balance and distribution of drug compound and its metabolites

• Structural characterization of metabolites by LC/MS/MS, LC/NMR, capillary NMR