Medicinal Chemistry

AMRI applies medicinal chemistry to modify the structure of a hit compound (or series of hit compounds) to synthesize new molecules with the end goal of discovering compounds suitable for progression into human clinical trials.

Over the past four years the Medicinal Chemistry group has completed over 93 projects in a wide variety of therapeutic areas.

In addition to its Medicinal chemistry capabilities AMRI also offers a range of other drug discovery and optimization services.

All of these services are fully integrated within the company allowing for a “one stop shop” approach towards outsourcing lead discovery and optimization efforts if so desired.

AMRI offers medicinal chemistry services at our United States, Singapore and India locations. Flexible business terms permit our customers to select resources at any or several (hybrid model) locations.

AMRI Advantage:

• Proven dependability and loyalty to partners, which include many of the world’s leading pharmaceutical and biotechnology companies
• A successful track record of helping customers establish intellectual property positions and advancing these compounds to clinical evaluation (AMRI has been named as inventors on +80 issued patents or filed applications and approximately 60 compounds have been nominated for clinical candidacy by our customers on work AMRI has conducted on their behalf)
• A skilled team of chemists, of which many are listed as inventors on multiple issued or pending composition of matter and chemical process patents
• The ability to use medicinal chemistry in tandem with state-of-the-art technologies
  

The medicinal chemistry group at AMRI has a wealth of lead discovery and optimization experience in a variety of therapeutic areas. Over the past four years the Medicinal Chemistry group has completed over 93 projects in a wide variety of therapeutic areas. A complete breakdown of the diversity of projects completed in the past four years is depicted in the graphic below:

Medicinal Chemistry Projects: 2003-2007: