Products and Services

Contract Drug Discovery

The Right Elements for Complex and Next-Generation Discovery R&D
 
Our Discovery & Development Services (DDS) business provides a comprehensive suite of drug discovery solutions. With more than 25 years of innovation in drug discovery and manufacturing, we combine broad target class coverage and access to state-of-the-art equipment to offer you a complete drug discovery experience.
 
Our Service Offerings Include:
  • Reagent Generation (Recombinant Proteins & Cell Lines)
  • Assay Development & Optimization (GPCRs, Kinases, other Enzymes, Ion Channels, Transporters)
  • High-Throughput Screening (HTS) with AMRI & Customer Compound Libraries using the PerkinElmer Cell Explorer HTS Platform
  • High-Content Screening & Phenotypic Screens
  • Biochemical & Cellular Screens
  • Compound & Sample Management
  • Hit Identification & Evaluation
  • Secondary Target & Safety Target Panels
  • Medicinal & Synthetic Chemistry (Hit to Lead & Lead Optimization)
  • Structure-Based Drug Design (with Harker Bio)
  • Custom Chemical Library Synthesis
  • Metabolic Stability
  • CYP Inhibition/Induction
  • Metabolite Identification
  • Synergies with Drug Discovery, Development, & Manufacturing Services at AMRI Global Sites